With ESXi 5 VMware made it very easy to create custom installation ISOs. I have been doing a lot of upgrades from ESXi 4.1 in our customer sites that have UCS, Nexus 1000v and PowerPath VE so I decided to create a custom ISO that includes the current UCS enic/fnic drivers and Nexus 1000v/PowerPath VE.
When I first started doing these upgrades I would remove the host from the Nexus 1000v VDS, uninstall Nexus 1000v VEM and uninstall PowerPath VE. After upgrading/rebuilding the host I would then use VUM to install Nexus 1000v VEM add it back to the VDS and then install PowerPath VE.